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How Does Levothyroxine Influence Calcium Levels In The Body?

levothyroxine and calcium levels

Levothyroxine, a synthetic hormone used to treat people with hypothyroidism, can influence calcium levels in the body if:

  • You take levothyroxine at the same time as your calcium supplements
  • Your calcium supplements lack Vitamin D, Vitamin K and Magnesium
  • You have not had your calcium levels tested medically and have been self-medicating
  • You don’t test your T3 and T4 regularly and continue your thyroid medication

If you are taking levothyroxine along with calcium supplements, please ensure you take it on an empty stomach with a full glass of water, and preferably at least 4 hours before or after you take your calcium supplements. It is advised that you do not take levothyroxine and calcium simultaneously, as it is seen that levothyroxine molecules stick to the calcium molecules and form a mixed substance which is not easily absorbed into your digestive tract.

People who do take levothyroxine and calcium simultaneously tend to develop reduced levels of thyroxine. You may need to have regular medical tests if you start taking levothyroxine. It is better to consult a physician while you are taking levothyroxine to ensure your calcium levels are not impacted.

To know more about the effects of levothyroxine on your body, please see, Does Thyroid Medication Increase Your Osteoporosis Risk?

Sharda Agarwal

Sharda Agarwal

Co-founder, Sepalika. Nutritional Therapy Practitioner (Cert Awaited), Nutritional Therapy Association, USA
Sharda Agarwal is a qualified Functional Nutrition Therapy Practitioner. She first used dietary supplements to overcome a debilitating migraine she suffered for years. Since then she has studied the subjects of nutrition and nutrients extensively. She uses this to manage the health of her family at home and with Sepalika.
Sharda Agarwal

Latest posts by Sharda Agarwal (see all)

1)     Jacob.J, Cherian.D,Chopra.S; The thyroid hormone, parathyroid hormone and vitamin D associated hypertension; Indian J Endocrinol Metab. 2011 Oct;15 (Suppl 4):S354-S360:

2)    Hoyle.G; Levothyroxine & Calcium;Livestrong. 2011 Aug;31 :





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This article is intended for informational purposes only. The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. strongly recommends that you consult a medical practitioner for implementing any of the above. Results may vary from person to person.

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