WHAT IS L-METHYLFOLATE Methylfolate is the biologically active, naturally occurring form of folate that is used for fundamental body functions like normal cell division and the synthesis of neurotransmitters and DNA. Unlike regular folic acid, Methylfolate has been shown to penetrate the blood-brain barrier, where it helps to support neurological health. HOW IS METHYLFOLATE BETTER THAN FOLIC ACID Those who take ordinary folic acid supplements, may not be experiencing its full spectrum of effects. This is because once ingested, not everyone converts folate to its biologically active form called 5-methyltetrahydrofolate (5-MTHF). Research shows that in a large proportion of the population, genetic enzyme deficiencies prevent the conversion of folate to 5-MTHF, leaving many vulnerable to low blood folate levels. A more useful approach is to take the bioactive folate 5-MTHF directly, which has been declassified as a drug and is now available as a dietary supplement. 5-MTHF has been shown to dramatically raise blood serum folate levels compared with folic acid supplementation. * L-5-MTHF is the most stable, bioavailable form of folic acid * This bioactive folate is up to seven times more bioavailable than folic acid. This greater bioavailability is especially important in people who have a genetic enzyme deficiency since it requires no conversion to become metabolically active. * Folate as L-methylfolate helps form healthy cells, especially red blood cells.