Sepalika Online Integrative Health Clinic

Using Functional Medicine to Reverse Chronic Diseases
(lab reports analysis, nutrition & lifestyle)

To know about our disease reversal programs

Diabetes Insipidus – When Kidneys Are Unable to Retain Water

diabetes insipidus

If you have been wondering what diabetes insipidus is, here are all your questions explained. Diabetes insipidus is not a form of diabetes, but is a rare condition where a person suffers from frequent urination and increased thirst. It’s called as diabetes insipidus because its symptoms are similar to that of diabetes. The condition is caused by inadequate output of vasopressin, the antidiuretic hormone or ADH, by the pituitary gland. It can also be caused by a lack of usual response by the kidney to ADH. The condition is less common than diabetes mellitus (type 1 and type 2) that result from insulin deficiency.

Types of Diabetes Insipidus

  • Central diabetes insipidus is caused due to damage to the pituitary gland that results in inadequate or total lack of output of antidiuretic hormone.
  • Nephrogenic diabetes insipidus is caused when the kidney is not able to respond to ADH.
  • Dipsogenic diabetes insipidus is caused due to a defect in the thirst mechanism, located in the hypothalamus (a portion of the brain). This form of diabetes insipidus may be confused with central diabetes insipidus.
  • Gestational diabetes insipidusu occurs only during pregnancy and is caused when an enzyme, named oxytocinase (P-LAP), released by the placenta affects the ADH.

Symptoms of Diabetes Insipidus

The main symptoms of diabetes insipidus are excessive urination and excessive thirst. The volume of urine passed out through the day can be anywhere between 3 to 20 liters. In some severe cases, it can go up to 30 liters. Secondary symptoms include vomiting and diarrhea due to dehydration, waking up frequently in the middle of the night to urinate, dry skin, weak muscles and constant fatigue.

How Is Diabetes Insipidus Diagnosed?

Since diabetes insipidus has symptoms like that of diabetes, special tests are needed for its diagnosis. Fluid deprivation test and monitoring of ADH levels in the blood are some ways to diagnose diabetes insipidus. Other tests include a urine analysis test, MRI tests of the brain to detect issues in the pituitary gland, and genetic screening for those who have a family history of diabetes insipidus.

Managing Diabetes Insipidus

One of the natural ways of managing diabetes insipidus are to follow a low salt and low protein diet. Salt increases thirst and protein foods increase urination. Also, it is advisable to include more water-based foods such as cucumbers, zucchini, and strawberries to ensure water going out through frequent urination is replaced.

Mahesh Jayaraman
Mahesh is a traditional acupressure therapist and health counselor. He is certified in Functional Nutrition from Washington State University and uses a wide array of healing modalities to guide his clients to vibrant health and well-being.
Mahesh Jayaraman

Latest posts by Mahesh Jayaraman (see all)

Diabetes insipidus: etiology, diagnosis, and therapy

Dipsogenic diabetes insipidus: report of a novel treatment strategy and literature review

Dipsogenic diabetes insipidus: a newly recognized syndrome caused by a selective defect in the osmoregulation of thirst.

Leave a Comment

Medical And General Disclaimer for
This article is intended for informational purposes only. The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. strongly recommends that you consult a medical practitioner for implementing any of the above. Results may vary from person to person.

Do I have Prediabetes?

Simply answer the questions on the Test Tool to see if you are at risk

Take The Test Now

Health Supplement Identifier

PCOD Treatment

Take Your First Step to a PCOD-Free Life!

This program is available only in India, for now

Know More
Our 5-Petal PCOD Treatment Program batch is full and participants are seeing wonderful results.

Get On The Waiting List

Sign up to be the first one to know when we begin our new batch!


Is there an alternative to popping pills?

Reclaim your health, naturally.